Remyelination Is Altered by Bone Morphogenic Protein Signaling in Demyelinated Lesions
نویسندگان
چکیده
منابع مشابه
Remyelination is altered by bone morphogenic protein signaling in demyelinated lesions.
Remyelination of the CNS involves the regeneration of mature oligodendrocytes by endogenous oligodendrocyte progenitor cells (OPCs). Previous studies have shown that bone morphogenic proteins (BMPs) inhibit the production of oligodendrocytes in the healthy CNS. However, there is currently no information on the influence of BMP signaling in vivo within demyelinated lesions of the brain or on sub...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2011
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.5859-10.2011